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Oncology Biomarkers

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Advanced Therapies Meet Biomarkers: What IO Teams Should Watch This Winter

Cell therapy, T cell engagers, cancer vaccines and intratumoural therapy are turning biomarkers into eligibility gates, manufacturing inputs and response…

swastik98 Oct 2026
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In Vivo CAR-T: Where the Field Stands and What It Means for Biomarkers

In vivo CAR-T programmes the patient's own T cells with a single IV dose, removing apheresis and manufacturing. Here is…

swastik98 Oct 2026
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Spatial Proteomics vs Spatial Transcriptomics for IO Biomarker Discovery

How spatial proteomics and spatial transcriptomics compare for immuno-oncology biomarker discovery: platforms, published evidence on checkpoint response, clinical translation hurdles…

swastik98 Oct 2026
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Immuno-Oncology Biomarker Trends to Watch Heading Into 2027

The five immuno-oncology biomarker trends that will shape strategy, trial design and partnering in 2027, and what to look for…

Anwesha Oct 2026
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Multiplex Immunoassay Platform Comparison 2027

A vendor-neutral comparison of soluble multiplex immunoassays and tissue multiplex immunofluorescence platforms for immuno-oncology biomarker teams, updated for the 2023…

Anwesha May 2026
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Biomarker Validation: Analytical vs Clinical Validation, Step by Step

A step-by-step guide to biomarker validation, from the context of use and fit-for-purpose analytical validation to clinical validation, clinical utility…

Anwesha May 2026
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Tumor Mutational Burden (TMB): From Research to Clinical Reality, 2027 Update

TMB-high at 10 mut/Mb became a tumour-agnostic indication in 2020, but the evidence since shows it predicts checkpoint benefit in…

Anwesha Apr 2026
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PD-L1 Testing in 2027: Assays, Cut-Offs and AI-Assisted Scoring

A refreshed guide to PD-L1 testing: the four FDA companion assays, TPS, CPS and TC/IC scoring, current US cut-offs by…

Anwesha Apr 2026

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